Healing Category
THE ACTIVATOR
GHRH(1-29) Analog
Sermorelin is the first 29 amino acids of growth hormone-releasing hormone (GHRH). Unlike synthetic HGH, it stimulates your pituitary to release your own growth hormone in natural pulsatile patterns. This preserves feedback loops and is safer for long-term use. It improves sleep, builds muscle, burns fat, and supports overall vitality. It's a cornerstone of anti-aging medicine.
Dose and schedule recommendations shown below come from The Peptide App Clinical Team. Research links are provided so readers can inspect the supporting evidence directly.
No. This profile records Sermorelin as not FDA approved and for research use only.
Review the regulatory and source details on this page for the current context.
Dose: Unvalidated regimen: 0.3 mg SubQ once nightly on 5 days/week.
Cycle: No clinically established cycle for this SubQ regimen.. This is clinical-team guidance for reference and does not replace individualized instructions from a licensed clinician.
This guide links to 1 curated or current research sources.
Reported side effects of Sermorelin include Injection site reactions, Flushing, Dizziness, and Headache.
They are reported or occasional reactions, not a prediction of what any one person will experience.
Sermorelin has an editorial safety grade of B (Good Safety).
Well tolerated with predictable side effects. Safer than exogenous HGH. Safety depends on dose, sourcing, health history and medical supervision, so this page does not call it safe for personal use.
The only sermorelin metabolite named in these laboratory studies is sermorelin(3-29)-NH2, which was used in in vitro work with spiked urine. In that study, sermorelin(3-29)-NH2 was used as a reference material, together with parent peptides, to develop a liquid chromatography-tandem mass spectrometry method for detecting GHRH administration. A separate in vitro study investigated the metabolism of sermorelin in fortified urine, alongside tesamorelin, CJC-1295, and CJC-1295 with drug affinity complex. That in vitro work identified nineteen major metabolites across the GHRH analogs, which were synthesized and characterized, but the facts do not state which of them come from sermorelin.
Binds GHRH receptors to trigger pulsatile GH release
Increases liver production of IGF-1
Improves deep sleep when GH peaks
Maintains natural somatostatin regulation
Adults with growth hormone deficiency · Those over 30 experiencing age-related decline · Athletes seeking improved recovery · People wanting anti-aging benefits without synthetic HGH
In-stock prices from 126 vendors, checked Oct 14, 2026.
Market evidence
We found certificates from some of the Sermorelin vendors we track. Based on the certificates our crawler found; vendors may publish more than we index. Research on this page describes the molecule. Vendor certificates concern particular market samples or batches; they do not change the research evidence or establish clinical safety, sterility, or suitability for use.
Certificate assessment
5 evaluated certificates
5 graded · 0 not graded · 0 in the A range.
Each result belongs to the named vendor’s certificate. Grades assess the document and its reported tests, not the vendor’s whole catalog or the safety of a product.
Automated checks can make mistakes. Open “Why this result?” for the reason and any review notice, and check the linked COA’s lot against your product. How grading works
5 evaluated records
Document grade
C10: No endotoxin (bacterial toxin) test is reported, and an injectable needs one, so the grade stops at D.
Document check: flag.
Lab record: matched.
Graded Oct 14, 2026 · Grader 0.4.9 · Policy 2026-10-07.2
Clear Cap/Bronze Crimp
Document grade
X2: The certificate's identity evidence (IDENTITY: Sermorelin -> Result: Sermorelin) can't confirm the peptide on its own; that needs mass spectrometry or a side-by-side match to a reference standard.
Document check: fail.
Lab record: not confirmed.
Graded Oct 14, 2026 · Grader 0.4.9 · Policy 2026-10-07.2
SE0002
Document grade
C10: No endotoxin (bacterial toxin) test is reported, and an injectable needs one, so the grade stops at D.
Document check: flag.
Lab record: matched.
Graded Oct 14, 2026 · Grader 0.4.9 · Policy 2026-10-07.2
CPSERM26051101
Document grade
X2: The certificate shows no identity test, so there is no evidence the vial contains the peptide on the label. Ask the vendor for a report that confirms identity by mass spectrometry.
Document check: fail.
Lab record: not confirmed.
Graded Oct 14, 2026 · Grader 0.4.9 · Policy 2026-10-07.2
FF0910
Document grade
C10: No endotoxin (bacterial toxin) test is reported, and an injectable needs one, so the grade stops at D.
Document check: flag.
Lab record: not confirmed.
Graded Oct 14, 2026 · Grader 0.4.9 · Policy 2026-10-07.2
AF88932011
| COA grade | Printed lab | Certificate | |||
|---|---|---|---|---|---|
| Kylo Peptides Lot: Clear Cap/Bronze Crimp | Document grade Why this result?C10: No endotoxin (bacterial toxin) test is reported, and an injectable needs one, so the grade stops at D. Document check: flag. Lab record: matched. Graded Oct 14, 2026 · Grader 0.4.9 · Policy 2026-10-07.2 | Freedom Diagnostics | May 31, 2026 | 99.4%99.0–99.49% | View COA |
| Valor Peptides Lot: SE0002 | Document grade Why this result?X2: The certificate's identity evidence (IDENTITY: Sermorelin -> Result: Sermorelin) can't confirm the peptide on its own; that needs mass spectrometry or a side-by-side match to a reference standard. Document check: fail. Lab record: not confirmed. Graded Oct 14, 2026 · Grader 0.4.9 · Policy 2026-10-07.2 | AccumarkLabs | May 29, 2026 | 98.83%Under 99% | View COA |
| Coffee & Peppers Lot: CPSERM26051101 | Document grade Why this result?C10: No endotoxin (bacterial toxin) test is reported, and an injectable needs one, so the grade stops at D. Document check: flag. Lab record: matched. Graded Oct 14, 2026 · Grader 0.4.9 · Policy 2026-10-07.2 | Freedom Diagnostics | May 16, 2026 | 99.74%99.5%+ | View COA |
| Atomik Labs Lot: FF0910 | Document grade Why this result?X2: The certificate shows no identity test, so there is no evidence the vial contains the peptide on the label. Ask the vendor for a report that confirms identity by mass spectrometry. Document check: fail. Lab record: not confirmed. Graded Oct 14, 2026 · Grader 0.4.9 · Policy 2026-10-07.2 | Janoshik | Sep 23, 2024Older record | 99.181%99.0–99.49% | View COA |
| Peptide Pros Lot: AF88932011 | Document grade Why this result?C10: No endotoxin (bacterial toxin) test is reported, and an injectable needs one, so the grade stops at D. Document check: flag. Lab record: not confirmed. Graded Oct 14, 2026 · Grader 0.4.9 · Policy 2026-10-07.2 | MZ Biolabs | May 2, 2022Older record | 100%99.5%+ | View COA |
The clinic network
Request a free connection to a peptide clinic, by telehealth or in person. A licensed clinician decides whether any treatment is right for you. How to get a Sermorelin prescription
Pure growth hormone boost without the unwanted side effects.
from $1.80/mg · 235 vendorsNº 006 / 006Short-acting GH pulse boost timed to your body's natural rhythm
from $2.65/mg · 188 vendorsNº 001 / 006Long-acting GH releaser, once or twice weekly
from $3.02/mg · 102 vendorsNº 002 / 006Understanding the muscle brake and how to release it
from $105 · 8 vendorsNº 003 / 006Muscle peptide for strength, endurance, and recovery
Full profileNº 004 / 006Extended-release IGF-1 for powerful muscle growth
from $30.10/mg · 148 vendorsNº 005 / 006
Combinations and evidence
Sermorelin and tesamorelin activate the same pituitary GHRH receptor, so stacking them acts like a higher single dose. No trial has tested the pair.
Compound evidence
Sermorelin raised GH in older adults and improved cognition in an 89-person, six-month trial. The trials had no fat-loss endpoint, and today's doses are lower.
Compound evidence
Tesamorelin cut visceral fat 10.9% versus 0.6% on placebo in a Phase 3 HIV trial. Sermorelin shares its receptor but has smaller trials, mostly in children.
