Metabolic Category
IGF-LR3
THE MUSCLE MAXIMIZER
Long R3 Insulin-like Growth Factor-1; LR3 IGF-1
IGF-LR3 is a modified version of IGF-1 with a much longer half-life. The modifications make it more potent and longer-lasting than natural IGF-1. It activates muscle satellite cells, promotes protein synthesis, and has powerful anabolic effects, which makes it popular among bodybuilders and those seeking muscle growth.
IGF-LR3 Evidence Snapshot
How these guides are reviewed- Regulatory status
- Not FDA approved · research use only
- Dosing guidance
- Reviewed by our clinical team
- Linked evidence
- 2 research sources
- Content updated
- Aug 28, 2026
Dose and schedule recommendations shown below come from The Peptide App Clinical Team. Research links are provided so readers can inspect the supporting evidence directly. Review the sources.
Quick Answers About IGF-LR3
Is IGF-LR3 FDA approved?
No. This profile records IGF-LR3 as not FDA approved and for research use only.
More context
Review the regulatory and source details on this page for the current context.
What dose does The Peptide App Clinical Team recommend for IGF-LR3?
Dose: 20-50 mcg daily.
More context
Schedule: daily. Cycle: 4-6 weeks on, 4 weeks off. This is clinical-team guidance for reference and does not replace individualized instructions from a licensed clinician.
What research supports this IGF-LR3 guide?
This guide links to 2 curated or current research sources.
More context
Open the research section to inspect the source titles, publication details, study types, and available abstracts directly.
Review the IGF-LR3 research sourcesStudied Effects & Mechanisms
IGF-1 Receptor Activation
Strongly activates IGF-1 receptors for growth signaling
Muscle Growth
Stimulates protein synthesis and satellite cell activation
Extended Half-Life
Modified structure resists binding proteins, lasting much longer
What the LR3 name describes
The Long R3 form of IGF-1 has two defining structural changes: a 13-amino-acid extension at the beginning of the chain and an arginine substitution at position 3 of the original IGF-1 sequence. Researchers have used this modified molecule to investigate how IGF proteins fold and form disulfide bonds. The name describes those structural changes, not a treatment schedule.
[Long-[Arg3]IGF-I folding study, 1999](https://pubmed.ncbi.nlm.nih.gov/9951525/)
Who is this for
Bodybuilders seeking muscle growth · Athletes wanting enhanced recovery · Those with muscle-wasting conditions · People wanting fat loss with muscle preservation
Further listening
1 recordingResearch-Market Price Snapshot
A compact market signal for this profile. The dedicated pricing page owns vendor, vial-size, and price-per-mg comparisons.
Updated Oct 5, 2026
- Vendors
- 2
- Listings
- 2
- Observed range
- $99–$301
Market evidence
IGF-LR3 product testing and COAs
Current certificates are on file for 39 of 126 vendors tracked in the IGF-LR3 market. Research on this page describes the molecule. Vendor certificates concern particular market samples or batches; they do not change the research evidence or establish clinical safety, sterility, or suitability for use.
IGF-LR3 Research
Live research temporarily unavailable
The live research feed did not return papers for this page. The curated references below remain available for crawlable source context.
Research references
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