THE REGENERATOR
TB-500
Promotes new blood vessel growth and reduces inflammation for stubborn injuries.
Also known as: Thymosin Beta-4 Fragment 17-23
Overview
TB-500 is a synthetic fragment of thymosin beta-4, a protein naturally involved in tissue repair and protection. It promotes cell migration, blood vessel formation (angiogenesis), and reduces inflammation and fibrosis. It's one of the most popular peptides for healing injuries - tendons, ligaments, muscles, and even cardiac tissue respond to its regenerative signals.
Key Benefits & Mechanisms
G-Actin Binding
Promotes cell migration by regulating cytoskeleton
Angiogenesis
Upregulates VEGF to create new blood vessels
Anti-Inflammatory
Inhibits NF-κB and reduces inflammatory cytokines
Anti-Fibrotic
Modulates TGF-β to reduce scarring
Dosing Guide
Dosage
2-5 mg per week, split into 2 injections
Schedule
twice_weekly
Cycle
4-8 weeks on, 4 weeks off
Pro Tip
Can load with 6 mg first week then reduce; inject subcutaneously
Safety Profile
Good Safety
Good
Generally well tolerated. Use with caution in cancer history.
Avoid in active cancers without medical supervision. May promote cell growth.
Possible Side Effects
What to Expect
Week 1
Reduced inflammation at injury sites
Week 2-3
Improved mobility and reduced pain
Week 4-6
Significant tissue repair and regeneration
Week 6-8
Near-complete healing for most injuries
Healing improvements often noticed within 1-2 weeks.
Who Is This For
Research References
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