THE JOINT REBUILDER
Sigumir
Rebuild your cartilage and relieve joint pain
Also known as: Cartilage Peptide Complex
Overview
Sigumir is a cartilage-derived bioregulator peptide that supports joint health and cartilage regeneration. It works by influencing gene expression in chondrocytes (cartilage cells) to boost collagen and proteoglycan production while reducing inflammatory enzymes that break down cartilage. It's particularly useful for osteoarthritis, joint injuries, and age-related cartilage degeneration.
Key Benefits & Mechanisms
Chondrocyte Gene Activation
Upregulates type II collagen and aggrecan genes
MMP Inhibition
Suppresses enzymes that break down cartilage
Growth Factor Support
Increases IGF-1 and TGF-β for cartilage repair
Synovial Support
Enhances synovial fluid and lubricin production
Dosing Guide
Dosage
10 mg daily (oral or subcutaneous)
Schedule
daily
Cycle
10-30 days on, 4 months off
Pro Tip
Take in the morning on an empty stomach for best absorption
Safety Profile
Excellent Safety
Excellent
No significant side effects reported. Well tolerated.
Caution in severe autoimmune joint diseases. Medical supervision recommended.
Possible Side Effects
What to Expect
Week 1-2
Peptide begins modulating cartilage gene expression
Week 2-3
Reduced joint inflammation and stiffness
Week 4
Improved joint mobility and comfort
Joint improvements may be gradual over 2-4 weeks.
Who Is This For
Research References
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