Cognitive Category
Vesugen
THE VESSEL PROTECTOR
A-7 Vascular Endothelium Bioregulator Peptide, KED
Vesugen is a synthetic tripeptide (Lys-Glu-Asp) that specifically targets the endothelium, the inner lining of your blood vessels. It reverses age-related declines in vascular elasticity, enhances nitric oxide production, and supports both cardiovascular and cognitive health by improving blood flow throughout the body.
Vesugen Evidence Snapshot
How these guides are reviewed- Regulatory status
- Not FDA approved · research use only
- Dosing guidance
- Reviewed by our clinical team
- Linked evidence
- 2 research sources
- Content updated
- Sep 15, 2026
Dose and schedule recommendations shown below come from The Peptide App Clinical Team. Research links are provided so readers can inspect the supporting evidence directly. Review the sources.
Quick Answers About Vesugen
Is Vesugen FDA approved?
No. This profile records Vesugen as not FDA approved and for research use only.
More context
Review the regulatory and source details on this page for the current context.
What dose does The Peptide App Clinical Team recommend for Vesugen?
Dose: No established SubQ regimen..
More context
Cycle: No established SubQ dosing cycle.. This is clinical-team guidance for reference and does not replace individualized instructions from a licensed clinician.
What research supports this Vesugen guide?
This guide links to 2 curated or current research sources.
More context
Open the research section to inspect the source titles, publication details, study types, and available abstracts directly.
Review the Vesugen research sourcesStudied Effects & Mechanisms
Endothelial Gene Activation
Upregulates eNOS, KLF2, VE-cadherin, and SIRT1 via epigenetic modification
Anti-Inflammatory
Suppresses NF-κB and STAT3 signaling, reducing adhesion molecules
Matrix Integrity
Upregulates elastin and collagen IV for vascular structure
Short-peptide research lineage
Vesugen is identified as Lys-Glu-Asp in a 2012 paper by Vladimir Khavinson and colleagues from the Pavlov Institute of Physiology in St. Petersburg. The study compared several short peptides in cell cultures. Lys-Glu-Asp, abbreviated KED, is a three-residue sequence; the related names used for other short peptides do not make their sequences interchangeable.
[Khavinson and colleagues, short-peptide cell-culture study, 2012](https://pubmed.ncbi.nlm.nih.gov/22808515/)
Who is this for
People with hypertension or vascular stiffness · Those recovering from stroke or ischemic events · Anyone wanting to protect blood vessels during aging · People with cognitive decline related to poor circulation · Those with microvascular disease or diabetes
Further listening
1 recordingResearch-Market Price Snapshot
A compact market signal for this profile. The dedicated pricing page owns vendor, vial-size, and price-per-mg comparisons.
Updated Oct 5, 2026
- Vendors
- 24
- Listings
- 25
- Observed range
- $35–$100
Market evidence
Vesugen product testing and COAs
Current certificates are on file for 12 of 26 vendors tracked in the Vesugen market. Research on this page describes the molecule. Vendor certificates concern particular market samples or batches; they do not change the research evidence or establish clinical safety, sterility, or suitability for use.
Vesugen Research
Live research temporarily unavailable
The live research feed did not return papers for this page. The curated references below remain available for crawlable source context.
Research references
The clinic network
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