Healing Category
PE-22-28
THE RAPID MOOD LIFTER
Spadin Analog; Shortened Spadin
PE-22-28 is a synthetic peptide derived from spadin that blocks TREK-1 potassium channels in the brain. This produces rapid antidepressant effects - often within days rather than the weeks typical of SSRIs. It promotes neurogenesis, protects neurons, and may help with stroke recovery. It's an exciting option for those seeking fast-acting mood support.
Key Benefits & Mechanisms
TREK-1 Blockade
Blocks potassium channels to stabilize neuronal membrane
Rapid Neurogenesis
Induces new brain cell growth within days
BDNF Upregulation
Increases brain-derived neurotrophic factor
Serotonin/Dopamine
Modulates monoamine neurotransmitter pathways
Who Is This For
Those seeking rapid mood improvement · People who haven't responded to traditional antidepressants · Stroke recovery patients · Those interested in neurogenesis · Anyone wanting faster-acting mood support
PE-22-28 Research Use Only Market Pricing
View all PE-22-28 price observationsUpdated Jun 12, 2026
Vendors
3
Listings
5
Low Price
$46
High Price
$81
Common Vial Sizes
PE-22-28 Research
Live research temporarily unavailable
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Research references
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