The Peptide AppField Guide · Healing SeriesSpecimen No. 37

Healing Category

LL-37

Name: LL-37: Uses, Evidence & Safety
Creator: The Peptide App
Published: 2026-01-27T18:38:35.818468+00:00

THE NATURAL ANTIBIOTIC

Cathelicidin Antimicrobial Peptide

LL-37 is part of your innate immune system: a natural antimicrobial peptide that kills bacteria, viruses, and fungi by punching holes in their membranes. It also modulates immune responses and promotes wound healing. Supplementing may help fight infections and support immune function.

LL-37

LL-37 Evidence Snapshot

How these guides are reviewed

Regulatory status: Not FDA approved · research use only
Dosing guidance: Reviewed by our clinical team
Linked evidence: 1 research sources
Content updated: Aug 28, 2026

Dose and schedule recommendations shown below come from The Peptide App Clinical Team. Research links are provided so readers can inspect the supporting evidence directly. Review the sources.

Quick Answers About LL-37

Is LL-37 FDA approved?

No. This profile records LL-37 as not FDA approved and for research use only.

More context

Review the regulatory and source details on this page for the current context.

What dose does The Peptide App Clinical Team recommend for LL-37?

Dose: Topical or injectable.

More context

Dosing varies by application. Schedule: daily. Cycle: As needed for infections or wounds. This is clinical-team guidance for reference and does not replace individualized instructions from a licensed clinician.

What research supports this LL-37 guide?

This guide links to 1 curated or current research sources.

More context

Open the research section to inspect the source titles, publication details, study types, and available abstracts directly.

Review the LL-37 research sources

Studied Effects & Mechanisms

Membrane Disruption

Punches holes in bacterial and viral membranes

Immune Modulation

Regulates inflammatory responses through TLR signaling

Wound Healing

Promotes angiogenesis and tissue repair

Who is this for

Those with recurring infections

Anyone recovering from wounds

Those with respiratory issues

Immune-compromised individuals

LL-37 Dosing

Dosage

Topical or injectable. Dosing varies by application

Schedule

daily

Cycle

As needed for infections or wounds

Clinical Team Note

Topical for wounds; injectable for systemic effects; clinical use under investigation

Get your exact syringe units with the LL-37 reconstitution calculator

Clinical Team Dosing Guidance

Reported Timeline

Hours

Direct antimicrobial action begins

Days

Immune modulation and wound healing initiation

Weeks

Tissue repair and infection resolution

Antimicrobial effects are rapid; wound healing over days to weeks.

Timelines summarize reported or expected patterns and are not guaranteed individual outcomes.

Clinical Safety Context

Good Safety

Editorial grade B · Good

SafetyBGood

FDA approval statusNo · research use only

Naturally occurring human peptide. Generally well-tolerated.

May stimulate inflammation if overused. Balance is important for immune function.

Possible side effects

Injection site reactions · Potential inflammation if overused

How to interpret safety grades

The Peptide App

Set up your LL-37 schedule

Dose reminders and your schedule, ready the moment you open the app.

Research-Market Price Snapshot

A compact market signal for this profile. The dedicated pricing page owns vendor, vial-size, and price-per-mg comparisons.

Updated Aug 29, 2026

Vendors: 49
Listings: 53
Observed range: $32–$129

Compare all LL-37 prices →

Market evidence

LL-37 product testing and COAs

Current certificates are on file for 28 of 49 vendors tracked in the LL-37 market. Research on this page describes the molecule. Vendor certificates concern particular market samples or batches; they do not change the research evidence or establish clinical safety, sterility, or suitability for use.

View vendor COAs and pricing →Testing database How to read a COA