Healing Category
LL-37
THE NATURAL ANTIBIOTIC
Cathelicidin Antimicrobial Peptide
LL-37 is part of your innate immune system: a natural antimicrobial peptide that kills bacteria, viruses, and fungi by punching holes in their membranes. It also modulates immune responses and promotes wound healing. Supplementing may help fight infections and support immune function.
LL-37 Evidence Snapshot
How these guides are reviewed- Regulatory status
- Not FDA approved · research use only
- Dosing guidance
- Reviewed by our clinical team
- Linked evidence
- 2 research sources
- Content updated
- Aug 28, 2026
Dose and schedule recommendations shown below come from The Peptide App Clinical Team. Research links are provided so readers can inspect the supporting evidence directly. Review the sources.
Quick Answers About LL-37
Is LL-37 FDA approved?
No. This profile records LL-37 as not FDA approved and for research use only.
More context
Review the regulatory and source details on this page for the current context.
What dose does The Peptide App Clinical Team recommend for LL-37?
Dose: Topical or injectable.
More context
Dosing varies by application. Schedule: daily. Cycle: As needed for infections or wounds. This is clinical-team guidance for reference and does not replace individualized instructions from a licensed clinician.
What research supports this LL-37 guide?
This guide links to 2 curated or current research sources.
More context
Open the research section to inspect the source titles, publication details, study types, and available abstracts directly.
Review the LL-37 research sourcesStudied Effects & Mechanisms
Membrane Disruption
Punches holes in bacterial and viral membranes
Immune Modulation
Regulates inflammatory responses through TLR signaling
Wound Healing
Promotes angiogenesis and tissue repair
From precursor protein to peptide
LL-37 is produced by cleavage of a larger precursor protein called hCAP18. A 2001 study of human neutrophils identified proteinase 3 as the enzyme responsible for releasing LL-37 from material secreted by those cells. This distinguishes the precursor protein from the shorter peptide released from it.
[Human hCAP18 processing study, 2001](https://pubmed.ncbi.nlm.nih.gov/11389039/)
Who is this for
Those with recurring infections · Anyone recovering from wounds · Those with respiratory issues · Immune-compromised individuals
Further listening
1 recordingResearch-Market Price Snapshot
A compact market signal for this profile. The dedicated pricing page owns vendor, vial-size, and price-per-mg comparisons.
Updated Oct 5, 2026
- Vendors
- 75
- Listings
- 81
- Observed range
- $30–$150
Market evidence
LL-37 product testing and COAs
Current certificates are on file for 33 of 83 vendors tracked in the LL-37 market. Research on this page describes the molecule. Vendor certificates concern particular market samples or batches; they do not change the research evidence or establish clinical safety, sterility, or suitability for use.
LL-37 Research
Live research temporarily unavailable
The live research feed did not return papers for this page. The curated references below remain available for crawlable source context.
Research references
The clinic network
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