Metabolic Category
Humanin
THE CELLULAR GUARDIAN
Mitochondrial-Derived Peptide (MDP)
Humanin is a tiny peptide encoded in your mitochondrial DNA that protects cells from death. It was discovered in Alzheimer's research and found to protect neurons, heart cells, and other tissues from damage. Your humanin levels drop by about 30% by age 40, making supplementation attractive for anti-aging.
Humanin Evidence Snapshot
How these guides are reviewed- Regulatory status
- Not FDA approved · research use only
- Dosing guidance
- Reviewed by our clinical team
- Linked evidence
- 2 research sources
- Content updated
- Aug 28, 2026
Dose and schedule recommendations shown below come from The Peptide App Clinical Team. Research links are provided so readers can inspect the supporting evidence directly. Review the sources.
Quick Answers About Humanin
Is Humanin FDA approved?
No. This profile records Humanin as not FDA approved and for research use only.
More context
Review the regulatory and source details on this page for the current context.
What dose does The Peptide App Clinical Team recommend for Humanin?
Dose: Research dosing varies.
More context
No established human protocol. Schedule: twice_weekly. Cycle: Experimental. As directed. This is clinical-team guidance for reference and does not replace individualized instructions from a licensed clinician.
What research supports this Humanin guide?
This guide links to 2 curated or current research sources.
More context
Open the research section to inspect the source titles, publication details, study types, and available abstracts directly.
Review the Humanin research sourcesWhat are the side effects of Humanin?
We don't list specific side effects for Humanin.
Is Humanin safe?
Humanin has an editorial safety grade of B (Good Safety).
More context
Well-tolerated in preclinical studies. Human safety data still emerging. Safety depends on dose, sourcing, health history and medical supervision, so this page does not call it safe for personal use.
Studied Effects & Mechanisms
Anti-Apoptotic
Blocks pro-death proteins to prevent cell death
Neuroprotection
Protects neurons from Alzheimer's-related damage
Mitochondrial Support
Improves mitochondrial function and reduces oxidative stress
The original Humanin discovery
Hashimoto, Niikura and colleagues at Keio University reported Humanin in 2001 after screening a brain-derived cDNA library. Their work identified a short coding sequence; a follow-up paper described its 24-residue peptide and the similarity of the associated cDNA to mitochondrial 16S ribosomal RNA. This history concerns the original Humanin sequence, not a substituted synthetic analogue.
[Hashimoto and colleagues, Humanin discovery, 2001](https://pubmed.ncbi.nlm.nih.gov/11371646/)
[Tajima and colleagues, Humanin sequence background, 2002](https://pubmed.ncbi.nlm.nih.gov/12009529/)
Who is this for
Those concerned about Alzheimer's · People wanting cardiovascular protection
Humanin price snapshot
In-stock prices from 16 vendors, checked Oct 14, 2026.
- Vendors
- 16
- Listings
- 17
- Observed range
- $48–$159
Market evidence
Humanin product testing and COAs
We found certificates from some of the Humanin vendors we track. Based on the certificates our crawler found; vendors may publish more than we index. Research on this page describes the molecule. Vendor certificates concern particular market samples or batches; they do not change the research evidence or establish clinical safety, sterility, or suitability for use.
Humanin research
The clinic network
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