Healing Category
Cardiogen
THE CARDIAC REGENERATOR
AEDR tetrapeptide; H-Ala-Glu-Asp-Arg-OH
Cardiogen is a synthetic tetrapeptide (AEDR) from the Khavinson family designed to support heart health. It stimulates cardiac progenitor cells to repair damaged heart tissue, reduces scarring after heart attacks, and may even have tumor-inhibiting properties. It's being studied for myocardial recovery and anti-aging.
Cardiogen Evidence Snapshot
How these guides are reviewed- Regulatory status
- Not FDA approved · research use only
- Dosing guidance
- No established regimen
- Linked evidence
- 1 research sources
- Content updated
- Sep 15, 2026
Research links are provided so readers can inspect the supporting evidence directly.
Quick Answers About Cardiogen
Is Cardiogen FDA approved?
No. This profile records Cardiogen as not FDA approved and for research use only.
More context
Review the regulatory and source details on this page for the current context.
What research supports this Cardiogen guide?
This guide links to 1 curated or current research sources.
What are the side effects of Cardiogen?
Reported side effects of Cardiogen include Minor injection site reactions.
More context
They are reported or occasional reactions, not a prediction of what any one person will experience.
Is Cardiogen safe?
Cardiogen has an editorial safety grade of A (Excellent Safety).
More context
Well-tolerated synthetic peptide with minimal side effects in studies. Safety depends on dose, sourcing, health history and medical supervision, so this page does not call it safe for personal use.
What is the proposed mechanism behind Cardiogen's cardioprotective activity?
The paper proposes that the previously reported cardioprotective activity of Cardiogen is determined by its capacity to activate synthesis of cytoskeletal and nuclear matrix proteins. In cultured cells, this protein synthesis activation is said to stimulate cell proliferation and reduce apoptosis.
Does Cardiogen affect nuclear matrix proteins such as lamin A and lamin C in laboratory studies?
In a laboratory study using cultured mouse embryonic fibroblasts, Cardiogen, also called H-Ala-Glu-Asp-Arg-OH, was reported to enhance the expression of the nuclear matrix proteins lamin A and lamin C. The same study reported that the increase was by 2-3 times for lamin A and lamin C, alongside enhanced expression of cytoskeletal proteins actin, tubulin and vimentin.
Studied Effects & Mechanisms
Cardiac Stem Cells
Stimulates heart progenitor cells to regenerate damaged tissue
Anti-Fibrotic
Reduces scar tissue formation in the heart
Anti-Apoptotic
Protects heart cells from programmed death
Who is this for
People recovering from heart events · Those with cardiac fibrosis or scarring · Aging individuals focused on heart health · Athletes wanting cardiac support · Anyone concerned about heart aging
Cardiogen price snapshot
In-stock prices from 30 vendors, checked Oct 14, 2026.
- Vendors
- 30
- Listings
- 30
- Observed range
- $36–$99
Market evidence
Cardiogen product testing and COAs
We found certificates from some of the Cardiogen vendors we track. Based on the certificates our crawler found; vendors may publish more than we index. Research on this page describes the molecule. Vendor certificates concern particular market samples or batches; they do not change the research evidence or establish clinical safety, sterility, or suitability for use.
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