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Nicholas Trigili · peptide stack

Nicholas Trigili's Summer Shred Stack

A plain-English breakdown of Nicholas Trigili's Summer Shred Stack as described by Nicholas Trigili in "The ONLY Peptide Stack You Need to Get Shredded Before Summer 2026", with the doses quoted exactly as stated in the video. This is an educational summary for research — it is not medical advice, a recommendation, or an endorsement of the protocol.

Nicholas Trigili · peptide stack

2peptides Nicholas Trigili names · 2 with doses

  1. Retatrutide

    Start 1-2 mg per week, titrate up to 2-3 mg per week; twice a week at most.

  2. MOTS-c

    Roughly 7 mg a week, split into doses.

Summarized from the video — educational only, not medical advice.

The video

Everything on this page is summarized from this video by Nicholas Trigili. Watch the original for full context.

Open the source video page →

The stack, item by item

Each item Nicholas Trigili mentions, with the dose exactly as stated in the video where one was given. Doses are quoted for attribution, not as instructions.

  • Retatrutide

    Triple-action peptide with 24% average weight loss in trials.

    As stated in the video

    Start 1-2 mg per week, titrate up to 2-3 mg per week; twice a week at most.

  • MOTS-c

    Exercise in a peptide. Boost metabolism without the treadmill

    As stated in the video

    Roughly 7 mg a week, split into doses.

How to read this stack

General, educational context only — not a schedule or an instruction to combine anything.

  • A stack is just the set of compounds a person says they use — it is not proof any of them work together or are safe together.
  • Doses shown are what the creator said on camera; they may not match labeling, may be mis-transcribed, and are not tailored to anyone.
  • Items like HGH and testosterone (TRT) are prescription hormones, not peptides, and carry their own separate risks and legal status.
  • Whether any of this is appropriate for a given person is a decision for a licensed professional who knows the full context.

Questions people ask

Answers stay educational rather than recommending a protocol.

What peptides are in Nicholas Trigili's Summer Shred Stack?

In "The ONLY Peptide Stack You Need to Get Shredded Before Summer 2026", Nicholas Trigili describes this stack as Retatrutide and MOTS-c. This page summarizes each one; the full profiles are linked where available.

What doses does Nicholas Trigili mention?

Retatrutide — Start 1-2 mg per week, titrate up to 2-3 mg per week; twice a week at most.; MOTS-c — Roughly 7 mg a week, split into doses.. These are quoted as stated in the video and are not a recommendation.

Is this stack safe to copy?

No page can tell you that. A stack that works for one person can be inappropriate or unsafe for another, some items are prescription hormones, and video doses may be inaccurate. Whether any protocol is appropriate is a decision for a licensed professional.

This page summarizes a third-party video for research and educational purposes only. It is not medical advice, does not diagnose, treat, prescribe, or tell you to start, stop, or combine any protocol, and it is not affiliated with or endorsed by Nicholas Trigili. Doses are quoted as stated in the source video and may be inaccurate. A licensed professional is the right person to evaluate any protocol.

Keep researching

Open a peptide profile, calculate a dose, or browse other creator stacks.