Healing Category
Kisspeptin-10
THE FERTILITY IGNITER
Metastin
Kisspeptin is the master switch for your reproductive hormone system. It triggers GnRH release from the hypothalamus, which then causes release of LH and FSH, ultimately controlling testosterone and estrogen. It's being studied for fertility treatments and may enhance libido and sexual function.
Kisspeptin-10 Evidence Snapshot
How these guides are reviewed- Regulatory status
- Not FDA approved · research use only
- Dosing guidance
- Reviewed by our clinical team
- Linked evidence
- 2 research sources
- Content updated
- Sep 15, 2026
Dose and schedule recommendations shown below come from The Peptide App Clinical Team. Research links are provided so readers can inspect the supporting evidence directly. Review the sources.
Quick Answers About Kisspeptin-10
Is Kisspeptin-10 FDA approved?
No. This profile records Kisspeptin-10 as not FDA approved and for research use only.
More context
Review the regulatory and source details on this page for the current context.
What dose does The Peptide App Clinical Team recommend for Kisspeptin-10?
Dose: 0.1 mg subcutaneously 2-3 times weekly (community-reported).
More context
Schedule: twice_weekly. Cycle: No clinically established cycle for this regimen. This is clinical-team guidance for reference and does not replace individualized instructions from a licensed clinician.
What research supports this Kisspeptin-10 guide?
This guide links to 2 curated or current research sources.
More context
Open the research section to inspect the source titles, publication details, study types, and available abstracts directly.
Review the Kisspeptin-10 research sourcesWhat are the side effects of Kisspeptin-10?
Reported side effects of Kisspeptin-10 include Temporary flushing and Headache from hormone surge.
More context
They are reported or occasional reactions, not a prediction of what any one person will experience.
Is Kisspeptin-10 safe?
Kisspeptin-10 has an editorial safety grade of B (Good Safety).
More context
Well-tolerated in research studies. Causes acute hormone surges. Safety depends on dose, sourcing, health history and medical supervision, so this page does not call it safe for personal use.
Studied Effects & Mechanisms
GnRH Trigger
Activates hypothalamic neurons to release GnRH
LH/FSH Surge
Causes pituitary to release luteinizing and follicle-stimulating hormones
Libido Enhancement
May influence sexual behavior pathways in the brain
The shorter kisspeptin fragment
Kisspeptin-10 corresponds to the ten amino acids at the C-terminal end of the longer kisspeptin sequence. The kisspeptin family comes from the KISS1 gene product. Its receptor was studied under the name GPR54; the International Union of Basic and Clinical Pharmacology later recommended the name kisspeptin receptor. The number 10 identifies the short fragment, not the whole precursor.
[Kotani and colleagues, kisspeptin identification, 2001](https://pubmed.ncbi.nlm.nih.gov/11457843/)
[IUPHAR kisspeptin receptor nomenclature, 2010](https://pmc.ncbi.nlm.nih.gov/articles/PMC2993257/)
Who is this for
Those with fertility issues · Anyone interested in libido enhancement · Researchers studying reproductive hormones · Those with hypogonadism
Kisspeptin-10 price snapshot
In-stock prices from 113 vendors, checked Oct 14, 2026.
- Vendors
- 113
- Listings
- 136
- Observed range
- $17–$765
Market evidence
Kisspeptin-10 product testing and COAs
We found certificates from some of the Kisspeptin-10 vendors we track. Based on the certificates our crawler found; vendors may publish more than we index. Research on this page describes the molecule. Vendor certificates concern particular market samples or batches; they do not change the research evidence or establish clinical safety, sterility, or suitability for use.
Kisspeptin-10 research
The clinic network
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