THE SATIETY SIGNAL

Cagrilintide

Grade B — Good

Long-acting appetite suppressant for serious weight loss

Also known as: Acylated amylin analog

Weight Management
Metabolic Modulator
Appetite Regulation

Overview

Cagrilintide is a modified version of amylin, a hormone your pancreas releases after eating. It tells your brain you're full, slows stomach emptying, and improves blood sugar control. Combined with GLP-1 drugs like semaglutide, it can produce dramatic weight loss results (up to 15% body weight).

Key Benefits & Mechanisms

Appetite Control

Activates satiety centers in the brain to reduce hunger

Gastric Slowing

Delays stomach emptying so you feel full longer

Blood Sugar

Suppresses glucagon and improves insulin sensitivity

Dosing Guide

Dosage

2.4 mg once weekly (subcutaneous)

Schedule

weekly

Cycle

8+ weeks (ongoing treatment)

Pro Tip

Often combined with semaglutide for enhanced effects; inject on same day each week

This peptide requires titration — start with a lower dose and increase gradually.

Safety Profile

B

Good Safety

Good

Well-tolerated in clinical trials. Being developed by Novo Nordisk.

Still in clinical development. Works best when combined with GLP-1 agonists.

Possible Side Effects

Mild nausea
Decreased appetite
Injection site irritation

What to Expect

Week 1

Reduced appetite and food intake

Week 4-8

Noticeable weight loss (3-5%)

Week 12+

Significant weight loss (10-15% with GLP-1 combo)

Appetite reduction within first week; significant weight loss by 8-12 weeks.

Who Is This For

People with obesity seeking medical weight loss
Type 2 diabetics needing better glucose control
Those who have plateaued on GLP-1 drugs alone
Anyone needing appetite suppression
People with metabolic syndrome

Research References

[1]Cagrilintide Phase 2 Trial Results - Novo Nordisk

Related Peptides

ACE-031

C

THE MUSCLE UNLEASHED

Block the muscle-limiting signal and unlock serious gains

BAM-15

B

THE CALORIE BURNER

Make your cells burn more fuel - mitochondrial uncoupling for fat loss

IGF-LR3

C

THE MUSCLE MAXIMIZER

Extended-release IGF-1 for powerful muscle growth

L-Carnitine

A

THE FAT TRANSPORTER

Fat-burning amino acid for energy and mitochondrial health

Mazdutide

C

THE DUAL ACTIVATOR

Next-gen weight loss with dual hormone action

Pancragen

A

THE PANCREAS PROTECTOR

Restore pancreatic function and improve blood sugar control

Ready to Start Your Peptide Journey?

Track your protocols, get guided reconstitution, and access our vetted vendor network — all in one app.

Download The Peptide App